ASCEplus EXOBALM
INTENSIVE DUAL-ACTION KOREAN RENEWAL BALM
ASCEplus EXOBALM
INTENSIVE DUAL-ACTION KOREAN RENEWAL BALM
WAYS TO SAVE:
Your Intensive Dual-Action Korean Renewal Balm :: After seeing how powerfully this formula restores skin after lasers and microneedling, we optimized it for daily use. This concentrated exosome complex works with soothing anti-inflammatory ingredients to reduce redness and sensitivity, while emollient hydrators and barrier lipids drench the skin in lasting moisture. A curated blend of peptides strengthens and amplifies exosome communication pathways, helping the skin rebuild, brighten, and protect itself every day. It’s the post-care GLO — now available anytime.
Experience the transformative power of ExoCoBio’s patented Rose Extracellular Vesicles (RSC-Exosome)—a Korean breakthrough in regenerative skincare technology, a cutting-edge innovation designed to elevate your skincare routine. This advanced formula targets visible signs of aging, promoting a smoother, firmer, and more youthful appearance.
ASCEplus EXOBALM is a regenerative cream that uses rose stem cell-derived exosomes, purified using their proprietary ExoSCRT™ technology, to promote skin healing and rejuvenation.
This product is designed for post-procedure recovery, as well as for regenerative daily anti-aging treatments. It features 2.5 billion rose exosomes along with other beneficial ingredients like growth factors, peptides, and antioxidants. Benefits include accelerating wound healing, reducing inflammation, improving skin tone, and strengthening the skin barrier.
Key components and benefits:

Rose Stem Cell Exosomes: The core ingredient, derived from the resilient Damask Rose and purified through ExoSCRT™ technology, delivers signals to skin cells to promote repair and renewal.
ExoSCRT™ Technology: A proprietary process used by ExoCoBio to isolate and purify high-purity exosomes from mass-cultured rose stem cells.
Comprehensive Formula: In addition to exosomes, the EXO Balm contains 6 peptides, NAD+, ExoCo Bio's ASCE+. Exobalm is a regenerative cream that uses rose stem cell-derived exosomes, purified using their proprietary ExoSCRT™ technology, to promote skin healing and rejuvenation.
Accelerated Healing: It is designed to speed up recovery after aesthetic procedures like laser resurfacing or microneedling, minimizing downtime, redness, and irritation.
Anti-aging and Brightening: The cream helps with skin rejuvenation, collagen increase, and skin brightening by reducing pigmentation.
Anti-inflammatory: It contains anti-inflammatory properties that help calm and soothe the skin.
Strengthened Skin Barrier: It works to improve and strengthen the skin's natural barrier function. Contains glutathione, and tranexamic acid to further enhance skin regeneration and brightening.
HOME CARE
- Put 1 (EXO CAPSULE) into 2 (W-FORMULA).
- Mix well with the enclosed spatula.
- Gently apply a thin, even layer of the mixture over the skin.
※ Keep refrigerated after opening. Do not freeze.

Key Ingredients
Lyophilized Exosomes (rose stem cell exosomes)
Peptides / Growth Factors: SH-Polypeptide-76, Pentapeptide-4, Hexapeptide-8, Oligopeptide-1/2, etc.
Hydrators: Sodium Hyaluronate, Trehalose, Mannitol
Barrier & Brightening Actives: Niacinamide, 3-O-Ethyl Ascorbic Acid, Tranexamic Acid, Squalane, Ceramide NP
Soothing Agents: Madecassoside, Allantoin, etc.
All Ingredients
Ingredients - 1 : EXO CAPSULE︱Water(Aqua), Sodium Hyaluronate, Methionine, Trehalose, Rosa Damascena Callus Extracellular Vesicles, Potassium Chloride, Ascorbic Acid, Magnesium Sulfate, Mannitol, Lysine, Tryptophan, Glutathione, Histidine, Rosa Damascena Flower Water, Glutamic Acid, Serine, 1,2-Hexanediol, Butylene Glycol, Nicotinamide Adenine Dinucleotide, Biotin, Maltodextrin, Coenzyme A, Sodium Citrate, Acetyl Hexapeptide-8, Nonapeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Disodium Flavine Adenine Dinucleotide, sh-Oligopeptide-2, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, sh-Oligopeptide-1, Citric Acid, sh-Polypeptide-1, sh-Polypeptide-76, sh-Polypeptide-3, Cyanocobalamin
Ingredients - 2 : W-FORMULA︱Water(Aqua), Caprylic/Capric Triglyceride, Glycerin, Squalane, Niacinamide, Tranexamic Acid, Helianthus Annuus (Sunflower) Seed Oil, 1,2-Hexanediol, Arachidyl Alcohol, Dipropylene Glycol, Dimethicone, Butyrospermum Parkii (Shea) Butter, Beeswax, Behenyl Alcohol, Cetearyl Alcohol, Carbomer, Arachidyl Glucoside, Palmitic Acid, Stearic Acid, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Tocopheryl Acetate, Allantoin, Panthenol, Ethylhexylglycerin, Caprylyl Glycol, Pentylene Glycol, Butylene Glycol, Sodium Hyaluronate, Adenosine, Disodium EDTA, Hydrogenated Lecithin, Sorbitan Isostearate, Citric Acid, Cholesterol, Ceramide NP, Myristic Acid, Glucose, Hydroxyphenyl Propamidobenzoic Acid, Arachidic Acid, Madecassoside, Glutathione, 3-O-Ethyl Ascorbic Acid, Lauric Acid
Caution︱For external use only, do not swallow. In case of accidental ingestion, seek professional assistance. Avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop using and consult a doctor if rash or irritation develops and lasts. Keep out of reach of children. Keep refrigerated after open. Do not freeze.
Prep matters — Always apply EXO Balm to clean, dry skin to maximize penetration of actives.
Timing is key — Use it immediately post-treatment or as part of your nightly recovery routine to help calm, hydrate, and protect the skin barrier.
Layer thoughtfully — Keep your regimen simple post-procedure. Apply EXO Balm before heavier moisturizers or occlusives, and avoid active acids or retinoids until skin feels balanced.
Consistency counts — Even outside of treatment windows, regular use can strengthen the skin barrier and keep inflammation in check, leading to healthier, more resilient skin over time.
Don’t skip sun protection — Shielding your skin daily is essential to support recovery and preserve results.





CLINICALLY PROVEN INGREDIENTS
Lyophilized Exosomes (Rose Stem Cell Exosomes): Advanced cellular messengers that support visible skin repair, renewal, and overall skin resilience
Peptides & Growth Factors (SH-Polypeptide-76, Pentapeptide-4, Hexapeptide-8, Oligopeptide-1/2): Targeted signals that promote firmer-looking skin, improved texture, and youthful vitality
Deep Hydrators (Sodium Hyaluronate, Trehalose, Mannitol): Deliver intense moisture to plump, smooth, and protect against dehydration
Barrier & Brightening Actives (Niacinamide, 3-O-Ethyl Ascorbic Acid, Tranexamic Acid, Squalane, Ceramide NP): Strengthen the skin barrier while enhancing clarity, radiance, and even tone
Soothing & Recovery Agents (Madecassoside, Allantoin): Calm visible irritation, reduce redness, and support post-treatment skin comfort





We created ASCEplus ExoBalm to give skin exactly what it needs to repair, restore, and strengthen itself—because true rejuvenation starts at the cellular level. Designed to nourish the skin barrier, calm visible stress, and support healthier-looking renewal, ExoBalm helps skin feel stronger, smoother, and more resilient with every use.
-Dr. Rajani

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FAQs
Exobalm FAQ
Yes. ExoBalm can be used to prep the skin before injectable and energy-based procedures. We refer to this as priming.
Priming typically starts about 7 days before a procedure and helps:
- Calm baseline inflammation
- Strengthen the skin barrier
- Improve overall skin resilience going into treatment
Always follow your provider’s specific pre-procedure instructions, especially regarding the day of treatment.
Post-procedure timing is provider-dependent. The extent and depth of the treatment being done.
Some providers allow ExoBalm to be restarted the same day, while others prefer waiting 24 hours. This depends on:
- Injection depth and technique
- Skin integrity
- Individual healing response
Always follow the guidance of the provider who performed your treatment.
Yes. ExoBalm works very well alongside retinoids and exfoliating acids, but application timing matters.
You have two safe options:
- Use them on different days, or
- Use ExoBalm in the morning and retinol or AHA at night
If combining in the same routine:
- Apply ExoBalm first on clean, dry skin
- Wait approximately 30 minutes
- Then apply retinol or AHA
This approach helps support the skin barrier and reduces irritation while still allowing actives to work effectively.
Yes. While originally developed for post-procedure recovery, ExoBalm is optimized for daily regenerative skincare and barrier support.
Apply ExoBalm to clean, dry skin before heavier moisturizers or occlusives.
Typical order:
Cleanse
ExoBalm
Moisturizer (if needed)
SPF in the morning
Yes. ExoBalm is commonly used around microneedling, lasers, RF microneedling, and other energy-based treatments to support recovery and reduce inflammation.
Post-treatment timing should follow provider guidance.
ExoBalm is formulated with barrier lipids, calming agents, and anti-inflammatory ingredients and is generally well tolerated. Patch testing is recommended for very reactive or compromised skin.
Yes if possible. Refrigeration is recommended after mixing, but it is not strictly required. It is stable at room temperature as well.
For many users, yes — especially during recovery phases. If additional moisture is needed, a simple moisturizer can be layered on top once ExoBalm has absorbed.
Exobalm is good for 3-4 months after it is mixed. We do recommend storing it in the refrigerator.
It is not mandatory. It really comes down to your personal preference. Dr. Rajani discusses this topic in this video:
https://youtu.be/aPL8CCQPxAY?si=8f7If-tbszC1PKJ-
- LSLinda S.Verified BuyerRated 5 out of 5 stars14 hours agoWow simply luxurious.
Exoblam cream is wonderful and refreshing.
It reminds me of Dr. Hauschka Rose Day Cream. Exoblam is much better due to it's anti-aging effects.
Was this helpful?Product Standouts Healing, UniqueRMRajani MD Beauty and Wellness39 seconds agoThank you so much for this review, Linda! We’re so glad our ASCEplus EXOBALM cream has stood out for you and that you’ve found it refreshing and luxurious for your skin. We appreciate you sharing this with us!
- APAmy P.Verified BuyerRated 5 out of 5 stars3 days agoExobalm
Luxuriously silky soft cream - I love it.
I use it as a middle layer cream between E2 and a thicker, heavier night cream.
For daytime, I just use it alone then sunscreen.
It’s is truly soft and silky, no scent, easy to love. I have purchased several of these.
Was this helpful?What is your skin type? DryWhat is your skin tone? WarmWhat are your skin concerns? Large Pores, Dryness, Fine Lines and Wrinkles, Facial Fat Loss, Collagen Loss, Jowls and/or SaggingHow old are you? 45-54What other Rajani MD products do you use? Devices, SkincareHow long have you used this product 60-90 daysProduct Standouts Fast Acting, Easy To Use, Healing, Hydrating, Great Ingredients - APAmy P.Verified BuyerRated 5 out of 5 stars3 days agoExobalm
I’m probably not using it as intended bc I use it every night over E2 cream - not as a prep.
I love how silky and soft it feels. Feels luxurious. No scent. Medium weight moisturizing, I do use another heavy moisturizer over top this at bedtime, only. Bought several of these so far.
Was this helpful?What is your skin type? DryWhat is your skin tone? WarmWhat are your skin concerns? Large Pores, Dryness, Fine Lines and Wrinkles, Facial Fat Loss, Collagen Loss, Jowls and/or SaggingHow old are you? 45-54What other Rajani MD products do you use? Devices, SkincareHow long have you used this product 60-90 daysProduct Standouts Fast Acting, Easy To Use, Healing, Hydrating, Great Ingredients - BWBrenda W.Verified BuyerRated 5 out of 5 stars2 weeks agoAmazing!
I've been using the ASCEplus Exobalm for a few weeks now. Truthfully, my skin was already in great shape because of the devices (including NEWA) I use. I didn't think it could get much better, but this has helped the 11's between my brows and small lines around my eyes. I'm 67 and Dr. Rajani helping me stay young!
Was this helpful?RMRajani MD Beauty and Wellness2 weeks agoThank you so much for sharing this, Brenda! We're so glad our ASCEplus EXOBALM has found a place in your routine, and we're honored that Dr. Rajani could be part of your skincare journey. Here's to feeling as radiant as you look!
- MSMary S.Verified BuyerRated 5 out of 5 stars1 month agoWonderful for after a laser treatment!
I splurge on this cream for before and after my laser treatments. I heal so much faster by using them!
Was this helpful? - CHcaroline h.Verified BuyerRated 5 out of 5 stars1 month agoa must have
This has become a must have for preping my skin whenever I do any needling and makes a great difference in the recovery quality.
Was this helpful? - RDRK D.Verified BuyerRated 5 out of 5 stars1 month agoEXOBALM
I have this on auto-ship because it is so amazing!! When it first came out and was available I of course watched the RajaniMD video on YouTube and thought okay sounds like I may need this! I had no idea it would become part my true routine that I can’t live without. This product is like a serum and it only takes a little bit, a thin layer to get great results!
I have a lot of textured skin on my lower face that looks much smoother! Just what I was looking for!
Was this helpful? - SstayspryVerified ReviewerRated 4 out of 5 stars3 months agoI like the product
would have continued using it had you kept it remotely affordable. This was $99 on sale and now its $120 on sale. This was literally two months ago. Bummer. Guess I wont be getting it again.
Was this helpful?RMRajani MD Beauty and Wellness3 months agoWe are so glad to hear you enjoyed ASCEplus EXOBALM and truly appreciate you taking the time to share your feedback. We completely understand how disappointing it can feel when pricing or promotional offers change, especially when you have found a skincare product you genuinely enjoy and want to continue using.
While promotions and special offers can vary throughout the year, we truly appreciate your honesty and feedback. We are incredibly grateful to have been part of your routine and hope to have the opportunity to welcome you back to ASCEplus EXOBALM in the future. ✨










