ASCEplus EXOBALM
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ASCEplus EXOBALM
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Your Intensive Dual-Action Korean Renewal Balm :: After seeing how powerfully this formula restores skin after lasers and microneedling, we optimized it for daily use. This concentrated exosome complex works with soothing anti-inflammatory ingredients to reduce redness and sensitivity, while emollient hydrators and barrier lipids drench the skin in lasting moisture. A curated blend of peptides strengthens and amplifies exosome communication pathways, helping the skin rebuild, brighten, and protect itself every day. It’s the post-care GLO — now available anytime.
Experience the transformative power of ExoCoBio’s patented Rose Extracellular Vesicles (RSC-Exosome)—a Korean breakthrough in regenerative skincare technology, a cutting-edge innovation designed to elevate your skincare routine. This advanced formula targets visible signs of aging, promoting a smoother, firmer, and more youthful appearance.
ASCEplus EXOBALM is a regenerative cream that uses rose stem cell-derived exosomes, purified using their proprietary ExoSCRT™ technology, to promote skin healing and rejuvenation.
This product is designed for post-procedure recovery, as well as for regenerative daily anti-aging treatments. It features 2.5 billion rose exosomes along with other beneficial ingredients like growth factors, peptides, and antioxidants. Benefits include accelerating wound healing, reducing inflammation, improving skin tone, and strengthening the skin barrier.
Key components and benefits:

Rose Stem Cell Exosomes: The core ingredient, derived from the resilient Damask Rose and purified through ExoSCRT™ technology, delivers signals to skin cells to promote repair and renewal.
ExoSCRT™ Technology: A proprietary process used by ExoCoBio to isolate and purify high-purity exosomes from mass-cultured rose stem cells.
Comprehensive Formula: In addition to exosomes, the EXO Balm contains 6 peptides, NAD+, ExoCo Bio's ASCE+. Exobalm is a regenerative cream that uses rose stem cell-derived exosomes, purified using their proprietary ExoSCRT™ technology, to promote skin healing and rejuvenation.
Accelerated Healing: It is designed to speed up recovery after aesthetic procedures like laser resurfacing or microneedling, minimizing downtime, redness, and irritation.
Anti-aging and Brightening: The cream helps with skin rejuvenation, collagen increase, and skin brightening by reducing pigmentation.
Anti-inflammatory: It contains anti-inflammatory properties that help calm and soothe the skin.
Strengthened Skin Barrier: It works to improve and strengthen the skin's natural barrier function. Contains glutathione, and tranexamic acid to further enhance skin regeneration and brightening.
HOME CARE
- Put 1 (EXO CAPSULE) into 2 (W-FORMULA).
- Mix well with the enclosed spatula.
- Gently apply a thin, even layer of the mixture over the skin.
※ Keep refrigerated after opening. Do not freeze.

Key Ingredients
Lyophilized Exosomes (rose stem cell exosomes)
Peptides / Growth Factors: SH-Polypeptide-76, Pentapeptide-4, Hexapeptide-8, Oligopeptide-1/2, etc.
Hydrators: Sodium Hyaluronate, Trehalose, Mannitol
Barrier & Brightening Actives: Niacinamide, 3-O-Ethyl Ascorbic Acid, Tranexamic Acid, Squalane, Ceramide NP
Soothing Agents: Madecassoside, Allantoin, etc.
All Ingredients
Ingredients - 1 : EXO CAPSULE︱Water(Aqua), Sodium Hyaluronate, Methionine, Trehalose, Rosa Damascena Callus Extracellular Vesicles, Potassium Chloride, Ascorbic Acid, Magnesium Sulfate, Mannitol, Lysine, Tryptophan, Glutathione, Histidine, Rosa Damascena Flower Water, Glutamic Acid, Serine, 1,2-Hexanediol, Butylene Glycol, Nicotinamide Adenine Dinucleotide, Biotin, Maltodextrin, Coenzyme A, Sodium Citrate, Acetyl Hexapeptide-8, Nonapeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Disodium Flavine Adenine Dinucleotide, sh-Oligopeptide-2, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, sh-Oligopeptide-1, Citric Acid, sh-Polypeptide-1, sh-Polypeptide-76, sh-Polypeptide-3, Cyanocobalamin
Ingredients - 2 : W-FORMULA︱Water(Aqua), Caprylic/Capric Triglyceride, Glycerin, Squalane, Niacinamide, Tranexamic Acid, Helianthus Annuus (Sunflower) Seed Oil, 1,2-Hexanediol, Arachidyl Alcohol, Dipropylene Glycol, Dimethicone, Butyrospermum Parkii (Shea) Butter, Beeswax, Behenyl Alcohol, Cetearyl Alcohol, Carbomer, Arachidyl Glucoside, Palmitic Acid, Stearic Acid, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Tocopheryl Acetate, Allantoin, Panthenol, Ethylhexylglycerin, Caprylyl Glycol, Pentylene Glycol, Butylene Glycol, Sodium Hyaluronate, Adenosine, Disodium EDTA, Hydrogenated Lecithin, Sorbitan Isostearate, Citric Acid, Cholesterol, Ceramide NP, Myristic Acid, Glucose, Hydroxyphenyl Propamidobenzoic Acid, Arachidic Acid, Madecassoside, Glutathione, 3-O-Ethyl Ascorbic Acid, Lauric Acid
Caution︱For external use only, do not swallow. In case of accidental ingestion, seek professional assistance. Avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop using and consult a doctor if rash or irritation develops and lasts. Keep out of reach of children. Keep refrigerated after open. Do not freeze.
Prep matters — Always apply EXO Balm to clean, dry skin to maximize penetration of actives.
Timing is key — Use it immediately post-treatment or as part of your nightly recovery routine to help calm, hydrate, and protect the skin barrier.
Layer thoughtfully — Keep your regimen simple post-procedure. Apply EXO Balm before heavier moisturizers or occlusives, and avoid active acids or retinoids until skin feels balanced.
Consistency counts — Even outside of treatment windows, regular use can strengthen the skin barrier and keep inflammation in check, leading to healthier, more resilient skin over time.
Don’t skip sun protection — Shielding your skin daily is essential to support recovery and preserve results.





CLINICALLY PROVEN INGREDIENTS
Lyophilized Exosomes (Rose Stem Cell Exosomes): Advanced cellular messengers that support visible skin repair, renewal, and overall skin resilience
Peptides & Growth Factors (SH-Polypeptide-76, Pentapeptide-4, Hexapeptide-8, Oligopeptide-1/2): Targeted signals that promote firmer-looking skin, improved texture, and youthful vitality
Deep Hydrators (Sodium Hyaluronate, Trehalose, Mannitol): Deliver intense moisture to plump, smooth, and protect against dehydration
Barrier & Brightening Actives (Niacinamide, 3-O-Ethyl Ascorbic Acid, Tranexamic Acid, Squalane, Ceramide NP): Strengthen the skin barrier while enhancing clarity, radiance, and even tone
Soothing & Recovery Agents (Madecassoside, Allantoin): Calm visible irritation, reduce redness, and support post-treatment skin comfort
Results You Can See
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We created ASCEplus ExoBalm to give skin exactly what it needs to repair, restore, and strengthen itself—because true rejuvenation starts at the cellular level. Designed to nourish the skin barrier, calm visible stress, and support healthier-looking renewal, ExoBalm helps skin feel stronger, smoother, and more resilient with every use.
-Dr. Rajani

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FAQs
Exobalm FAQ
Yes. ExoBalm can be used to prep the skin before injectable and energy-based procedures. We refer to this as priming.
Priming typically starts about 7 days before a procedure and helps:
- Calm baseline inflammation
- Strengthen the skin barrier
- Improve overall skin resilience going into treatment
Always follow your provider’s specific pre-procedure instructions, especially regarding the day of treatment.
Post-procedure timing is provider-dependent. The extent and depth of the treatment being done.
Some providers allow ExoBalm to be restarted the same day, while others prefer waiting 24 hours. This depends on:
- Injection depth and technique
- Skin integrity
- Individual healing response
Always follow the guidance of the provider who performed your treatment.
Yes. ExoBalm works very well alongside retinoids and exfoliating acids, but application timing matters.
You have two safe options:
- Use them on different days, or
- Use ExoBalm in the morning and retinol or AHA at night
If combining in the same routine:
- Apply ExoBalm first on clean, dry skin
- Wait approximately 30 minutes
- Then apply retinol or AHA
This approach helps support the skin barrier and reduces irritation while still allowing actives to work effectively.
Yes. While originally developed for post-procedure recovery, ExoBalm is optimized for daily regenerative skincare and barrier support.
Apply ExoBalm to clean, dry skin before heavier moisturizers or occlusives.
Typical order:
Cleanse
ExoBalm
Moisturizer (if needed)
SPF in the morning
Yes. ExoBalm is commonly used around microneedling, lasers, RF microneedling, and other energy-based treatments to support recovery and reduce inflammation.
Post-treatment timing should follow provider guidance.
ExoBalm is formulated with barrier lipids, calming agents, and anti-inflammatory ingredients and is generally well tolerated. Patch testing is recommended for very reactive or compromised skin.
Yes if possible. Refrigeration is recommended after mixing, but it is not strictly required. It is stable at room temperature as well.
For many users, yes — especially during recovery phases. If additional moisture is needed, a simple moisturizer can be layered on top once ExoBalm has absorbed.
Exobalm is good for 3-4 months after it is mixed. We do recommend storing it in the refrigerator.
It is not mandatory. It really comes down to your personal preference. Dr. Rajani discusses this topic in this video:
https://youtu.be/aPL8CCQPxAY?si=8f7If-tbszC1PKJ-
- PPPamela P.Verified BuyerRated 5 out of 5 stars2 days agoI love this product!
I’m on my second jar and I believe it’s helping hydrate my skin. I expect more results the longer I use it.
Was this helpful?What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Large Pores, Fine Lines and Wrinkles, Collagen Loss, Jowls and/or Sagging, Neck ConcernsHow old are you? 75+What other Rajani MD products do you use? Devices, Skincare, SupplementsHow long have you used this product 60-90 daysProduct Standouts Easy To Use, Unique, Hydrating, Healing, Gentle - DDDiana D.Verified BuyerRated 5 out of 5 stars5 days agoLove The Exobalm
This product feels wonderful on my skin,, since I have sensitive skin it's not easy finding things that feel good.....and makes a big difference in the texture and appearance also...I have purchased a few times even though it's a little pricey for me,, it's well worth it.
Was this helpful?What is your skin type? SensitiveWhat is your skin tone? MediumWhat are your skin concerns? Dryness, Facial Fat Loss, Collagen LossHow old are you? 65-74What other Rajani MD products do you use? Skincare, DevicesHow long have you used this product Longer than 90 daysProduct Standouts Gentle, Hydrating, Healing, Great Ingredients, Easy To Use - SCS C.Verified BuyerRated 5 out of 5 stars5 days agoWorth Every Dollar
I am fan of exobalm. My skin absolutely thrives when it is used. At first, I was over zealous using it. Then I realized a little goes a long way. I have incorporated it into my nightly routine. Oh, did I say I ABSOLUTELY am a huge fan! Try it ladies, it is the BEST!
Was this helpful?What is your skin type? SensitiveWhat is your skin tone? DarkWhat are your skin concerns? Facial Fat Loss, Neck Concerns, Collagen Loss, Fine Lines and WrinklesWhat other Rajani MD products do you use? Devices, Skincare, SupplementsHow long have you used this product Longer than 90 daysProduct Standouts Easy To Use, Unique, Great Ingredients, Gentle, Hydrating - RLRosie L.Verified BuyerRated 4 out of 5 stars1 week agoExo lightweight hydrating
This is really interesting. I am new to exosome and so far I’m really love it. Lightweight hydrating skin is looking good.😍
Was this helpful?What is your skin type? CombinationWhat is your skin tone? MediumWhat are your skin concerns? Eye Concerns, Inflammation and Redness, Jowls and/or SaggingHow old are you? 35-44What other Rajani MD products do you use? Devices, Skincare, SupplementsHow long have you used this product Longer than 90 daysProduct Standouts Fast Acting, Easy To Use, Hydrating, Unique, Dramatic Results - PPPamela P.Verified BuyerRated 5 out of 5 stars2 weeks agoA must have cream
Oh I love this cream! I’ve used it and I’m on my second jar.
Was this helpful?What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Large Pores, Fine Lines and Wrinkles, Collagen Loss, Jowls and/or Sagging, Neck ConcernsHow old are you? 75+What other Rajani MD products do you use? Devices, Skincare, SupplementsHow long have you used this product 30-60 daysProduct Standouts Easy To Use, Unique, Gentle, Healing, Hydrating - JBJoanna B.Verified BuyerRated 5 out of 5 stars2 weeks agoLove this
Use this all the time after applying Spicules.
Was this helpful?What is your skin type? CombinationWhat is your skin tone? MediumWhat are your skin concerns? Fine Lines and Wrinkles, Jowls and/or Sagging, Collagen Loss, Eye Concerns, Neck ConcernsHow old are you? 55-64What other Rajani MD products do you use? Devices, SkincareHow long have you used this product 30-60 daysProduct Standouts Unique, Easy To UseRMRajani MD Beauty and Wellness2 weeks agoWe are so glad you are loving the ASCEplus EXOBALM and that you’ve found the perfect place for it in your routine! Thank you for sharing this with us, Joanna!
- NGNancy G.Verified BuyerRated 5 out of 5 stars3 weeks agoHydrated and smooth
My skin texture is smooth and hydrated. It such a more youthful healthy look!
Was this helpful?How long have you used this product Less than 30 days - JLJoyce L.Verified BuyerRated 5 out of 5 stars3 weeks agoExobalm
Love love love
Was this helpful?What is your skin type? CombinationWhat is your skin tone? MediumWhat are your skin concerns? Fine Lines and Wrinkles, Collagen Loss, Jowls and/or Sagging, Neck Concerns, Facial Fat Loss, Eye ConcernsHow old are you? 65-74What other Rajani MD products do you use? Devices, Skincare, SupplementsHow long have you used this product 60-90 daysProduct Standouts Unique, Fast Acting, Hydrating, Healing, Easy To Use










