ASCEplus EXOBALM
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ASCEplus EXOBALM
ALL SALES ARE FINAL
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Your Intensive Dual-Action Korean Renewal Balm :: After seeing how powerfully this formula restores skin after lasers and microneedling, we optimized it for daily use. This concentrated exosome complex works with soothing anti-inflammatory ingredients to reduce redness and sensitivity, while emollient hydrators and barrier lipids drench the skin in lasting moisture. A curated blend of peptides strengthens and amplifies exosome communication pathways, helping the skin rebuild, brighten, and protect itself every day. It’s the post-care GLO — now available anytime.
Experience the transformative power of ExoCoBio’s patented Rose Extracellular Vesicles (RSC-Exosome)—a Korean breakthrough in regenerative skincare technology, a cutting-edge innovation designed to elevate your skincare routine. This advanced formula targets visible signs of aging, promoting a smoother, firmer, and more youthful appearance.
ASCEplus EXOBALM is a regenerative cream that uses rose stem cell-derived exosomes, purified using their proprietary ExoSCRT™ technology, to promote skin healing and rejuvenation.
This product is designed for post-procedure recovery, as well as for regenerative daily anti-aging treatments. It features 2.5 billion rose exosomes along with other beneficial ingredients like growth factors, peptides, and antioxidants. Benefits include accelerating wound healing, reducing inflammation, improving skin tone, and strengthening the skin barrier.
Key components and benefits:

Rose Stem Cell Exosomes: The core ingredient, derived from the resilient Damask Rose and purified through ExoSCRT™ technology, delivers signals to skin cells to promote repair and renewal.
ExoSCRT™ Technology: A proprietary process used by ExoCoBio to isolate and purify high-purity exosomes from mass-cultured rose stem cells.
Comprehensive Formula: In addition to exosomes, the EXO Balm contains 6 peptides, NAD+, ExoCo Bio's ASCE+. Exobalm is a regenerative cream that uses rose stem cell-derived exosomes, purified using their proprietary ExoSCRT™ technology, to promote skin healing and rejuvenation.
Accelerated Healing: It is designed to speed up recovery after aesthetic procedures like laser resurfacing or microneedling, minimizing downtime, redness, and irritation.
Anti-aging and Brightening: The cream helps with skin rejuvenation, collagen increase, and skin brightening by reducing pigmentation.
Anti-inflammatory: It contains anti-inflammatory properties that help calm and soothe the skin.
Strengthened Skin Barrier: It works to improve and strengthen the skin's natural barrier function. Contains glutathione, and tranexamic acid to further enhance skin regeneration and brightening.
HOME CARE
- Put 1 (EXO CAPSULE) into 2 (W-FORMULA).
- Mix well with the enclosed spatula.
- Gently apply a thin, even layer of the mixture over the skin.
※ Keep refrigerated after opening. Do not freeze.

Key Ingredients
Lyophilized Exosomes (rose stem cell exosomes)
Peptides / Growth Factors: SH-Polypeptide-76, Pentapeptide-4, Hexapeptide-8, Oligopeptide-1/2, etc.
Hydrators: Sodium Hyaluronate, Trehalose, Mannitol
Barrier & Brightening Actives: Niacinamide, 3-O-Ethyl Ascorbic Acid, Tranexamic Acid, Squalane, Ceramide NP
Soothing Agents: Madecassoside, Allantoin, etc.
All Ingredients
Ingredients - 1 : EXO CAPSULE︱Water(Aqua), Sodium Hyaluronate, Methionine, Trehalose, Rosa Damascena Callus Extracellular Vesicles, Potassium Chloride, Ascorbic Acid, Magnesium Sulfate, Mannitol, Lysine, Tryptophan, Glutathione, Histidine, Rosa Damascena Flower Water, Glutamic Acid, Serine, 1,2-Hexanediol, Butylene Glycol, Nicotinamide Adenine Dinucleotide, Biotin, Maltodextrin, Coenzyme A, Sodium Citrate, Acetyl Hexapeptide-8, Nonapeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Disodium Flavine Adenine Dinucleotide, sh-Oligopeptide-2, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, sh-Oligopeptide-1, Citric Acid, sh-Polypeptide-1, sh-Polypeptide-76, sh-Polypeptide-3, Cyanocobalamin
Ingredients - 2 : W-FORMULA︱Water(Aqua), Caprylic/Capric Triglyceride, Glycerin, Squalane, Niacinamide, Tranexamic Acid, Helianthus Annuus (Sunflower) Seed Oil, 1,2-Hexanediol, Arachidyl Alcohol, Dipropylene Glycol, Dimethicone, Butyrospermum Parkii (Shea) Butter, Beeswax, Behenyl Alcohol, Cetearyl Alcohol, Carbomer, Arachidyl Glucoside, Palmitic Acid, Stearic Acid, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Tocopheryl Acetate, Allantoin, Panthenol, Ethylhexylglycerin, Caprylyl Glycol, Pentylene Glycol, Butylene Glycol, Sodium Hyaluronate, Adenosine, Disodium EDTA, Hydrogenated Lecithin, Sorbitan Isostearate, Citric Acid, Cholesterol, Ceramide NP, Myristic Acid, Glucose, Hydroxyphenyl Propamidobenzoic Acid, Arachidic Acid, Madecassoside, Glutathione, 3-O-Ethyl Ascorbic Acid, Lauric Acid
Caution︱For external use only, do not swallow. In case of accidental ingestion, seek professional assistance. Avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop using and consult a doctor if rash or irritation develops and lasts. Keep out of reach of children. Keep refrigerated after open. Do not freeze.
Prep matters — Always apply EXO Balm to clean, dry skin to maximize penetration of actives.
Timing is key — Use it immediately post-treatment or as part of your nightly recovery routine to help calm, hydrate, and protect the skin barrier.
Layer thoughtfully — Keep your regimen simple post-procedure. Apply EXO Balm before heavier moisturizers or occlusives, and avoid active acids or retinoids until skin feels balanced.
Consistency counts — Even outside of treatment windows, regular use can strengthen the skin barrier and keep inflammation in check, leading to healthier, more resilient skin over time.
Don’t skip sun protection — Shielding your skin daily is essential to support recovery and preserve results.





CLINICALLY PROVEN INGREDIENTS
Lyophilized Exosomes (Rose Stem Cell Exosomes): Advanced cellular messengers that support visible skin repair, renewal, and overall skin resilience
Peptides & Growth Factors (SH-Polypeptide-76, Pentapeptide-4, Hexapeptide-8, Oligopeptide-1/2): Targeted signals that promote firmer-looking skin, improved texture, and youthful vitality
Deep Hydrators (Sodium Hyaluronate, Trehalose, Mannitol): Deliver intense moisture to plump, smooth, and protect against dehydration
Barrier & Brightening Actives (Niacinamide, 3-O-Ethyl Ascorbic Acid, Tranexamic Acid, Squalane, Ceramide NP): Strengthen the skin barrier while enhancing clarity, radiance, and even tone
Soothing & Recovery Agents (Madecassoside, Allantoin): Calm visible irritation, reduce redness, and support post-treatment skin comfort
Results You Can See
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We created ASCEplus ExoBalm to give skin exactly what it needs to repair, restore, and strengthen itself—because true rejuvenation starts at the cellular level. Designed to nourish the skin barrier, calm visible stress, and support healthier-looking renewal, ExoBalm helps skin feel stronger, smoother, and more resilient with every use.
-Dr. Rajani

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FAQs
Exobalm FAQ
Yes. ExoBalm can be used to prep the skin before injectable and energy-based procedures. We refer to this as priming.
Priming typically starts about 7 days before a procedure and helps:
- Calm baseline inflammation
- Strengthen the skin barrier
- Improve overall skin resilience going into treatment
Always follow your provider’s specific pre-procedure instructions, especially regarding the day of treatment.
Post-procedure timing is provider-dependent. The extent and depth of the treatment being done.
Some providers allow ExoBalm to be restarted the same day, while others prefer waiting 24 hours. This depends on:
- Injection depth and technique
- Skin integrity
- Individual healing response
Always follow the guidance of the provider who performed your treatment.
Yes. ExoBalm works very well alongside retinoids and exfoliating acids, but application timing matters.
You have two safe options:
- Use them on different days, or
- Use ExoBalm in the morning and retinol or AHA at night
If combining in the same routine:
- Apply ExoBalm first on clean, dry skin
- Wait approximately 30 minutes
- Then apply retinol or AHA
This approach helps support the skin barrier and reduces irritation while still allowing actives to work effectively.
Yes. While originally developed for post-procedure recovery, ExoBalm is optimized for daily regenerative skincare and barrier support.
Apply ExoBalm to clean, dry skin before heavier moisturizers or occlusives.
Typical order:
Cleanse
ExoBalm
Moisturizer (if needed)
SPF in the morning
Yes. ExoBalm is commonly used around microneedling, lasers, RF microneedling, and other energy-based treatments to support recovery and reduce inflammation.
Post-treatment timing should follow provider guidance.
ExoBalm is formulated with barrier lipids, calming agents, and anti-inflammatory ingredients and is generally well tolerated. Patch testing is recommended for very reactive or compromised skin.
Yes if possible. Refrigeration is recommended after mixing, but it is not strictly required. It is stable at room temperature as well.
For many users, yes — especially during recovery phases. If additional moisture is needed, a simple moisturizer can be layered on top once ExoBalm has absorbed.
Exobalm is good for 3-4 months after it is mixed. We do recommend storing it in the refrigerator.
It is not mandatory. It really comes down to your personal preference. Dr. Rajani discusses this topic in this video:
https://youtu.be/aPL8CCQPxAY?si=8f7If-tbszC1PKJ-
- LCLynn C.Verified BuyerRated 5 out of 5 stars16 hours agoMust have
I love using this cream after my RF. It calms my sensitive skin and makes my skin feel silky and hydrated.
Was this helpful?What is your skin type? SensitiveWhat is your skin tone? MediumWhat are your skin concerns? Pigmentation, Dark Spots or Melasma, Dryness, Fine Lines and Wrinkles, Sun Damage, Facial Fat Loss, Collagen Loss, Jowls and/or Sagging, Neck ConcernsHow old are you? 65-74What other Rajani MD products do you use? Devices, Skincare, SupplementsHow long have you used this product 30-60 daysProduct Standouts Dramatic Results, Healing, Hydrating - MAMarisa A.Verified BuyerRated 5 out of 5 stars1 week agoSoft cream
Just started using this cream a few days before and after starting my plasmasomes microneedling kit . It’s so soft on the skin feeling so smooth.
I at first won a jar on a live give away and then bought another on sale. Would buy again but only on sale because it’s pricey.
Was this helpful?What is your skin type? NormalWhat is your skin tone? MediumWhat are your skin concerns? Fine Lines and Wrinkles, Sun Damage, Eye Concerns, Facial Fat LossHow old are you? 45-54What other Rajani MD products do you use? Devices, SkincareHow long have you used this product Less than 30 daysProduct Standouts Easy To Use, Gentle, Great Ingredients, Hydrating - JPJack P. D.Verified BuyerRated 5 out of 5 stars1 week agoGame changed
Have been using for a year now. Will never go without.
Was this helpful?What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Jowls and/or Sagging, Collagen Loss, Facial Fat Loss, Neck Concerns, Eye Concerns, Fine Lines and Wrinkles, Large PoresHow old are you? 55-64What other Rajani MD products do you use? Devices, SkincareHow long have you used this product Longer than 90 daysProduct Standouts Smells Great, Hydrating, Great Ingredients - CECarina E.Verified BuyerRated 4 out of 5 stars1 week agoCream
I think it is very good cream.
Was this helpful? - CPConcetta P.Verified BuyerRated 5 out of 5 stars1 week agoGreat moisture
I love this product. It delivers a great moisture especially after using the plasmasomes with microneedling. I see a difference in the quality of my skin very few lines at 54 years old! My husband used this on his surgery scars after stitch removal and the healing was phenominal.
Was this helpful?What is your skin type? DryWhat is your skin tone? FairWhat are your skin concerns? Breakouts and/or Acne, Pigmentation, Dark Spots or Melasma, Inflammation and Redness, Dryness, Fine Lines and Wrinkles, Jowls and/or Sagging, Sun Damage, Neck Concerns, Eye Concerns, Collagen LossHow old are you? 45-54What other Rajani MD products do you use? Devices, SkincareHow long have you used this product Longer than 90 daysProduct Standouts Hydrating, Gentle, Healing, Great Ingredients, Unique - ABANDREA B.Verified BuyerRated 5 out of 5 stars1 week agoThis is amazing
I just started using this product but I am in love with it! It is well worth the money and I am excited to see results.
Was this helpful?What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Breakouts and/or Acne, Pigmentation, Dark Spots or Melasma, Fine Lines and Wrinkles, Blackheads, Sun DamageHow old are you? 55-64What other Rajani MD products do you use? Skincare, DevicesHow long have you used this product Less than 30 daysProduct Standouts Easy To Use - CPChris P.Verified BuyerRated 4 out of 5 stars1 week agoLove this
Since I started using this when it was first introduced, my skin is stronger/healthier and melasma is clearer. I feel that the healing properties are working because my skin can now tolerate the DEJ serum without flaking. I primarily use this over the spicule serum every other night.
Was this helpful?What is your skin type? CombinationWhat is your skin tone? MediumWhat are your skin concerns? Breakouts and/or Acne, Pigmentation, Dark Spots or Melasma, Inflammation and Redness, Large Pores, Fine Lines and WrinklesHow old are you? 65-74What other Rajani MD products do you use? Devices, Skincare, SupplementsHow long have you used this product Longer than 90 daysProduct Standouts Gentle, Healing - CACelest A.Verified BuyerRated 5 out of 5 stars1 week agoASCE
Used ASCE EXOBALM after having a Cool Peel, I believe that it helped with the healing process. It’s a great product.!
Was this helpful?What is your skin type? CombinationWhat is your skin tone? MediumWhat are your skin concerns? Collagen Loss, Neck Concerns, Jowls and/or SaggingHow old are you? 75+What other Rajani MD products do you use? SkincareHow long have you used this product Longer than 90 daysProduct Standouts Great Ingredients, Healing, HydratingRMRajani MD Beauty and Wellness1 week agoWe’re so happy you like the ASCEplus EXOBALM, Celest! We appreciate you taking the time to share your experience with us, and we’re glad to have you in the Rajani MD community!









































