Skip to content

LABOR DAY SALE - USE CODE: LABORDAY

FREE SHIPPING AVAILABLE ON US ORDERS*

FREE GIFT WITH EVERY ORDER!

SAVE WITH SUBSCRIPTIONS. RESCHEDULE, SKIP, CANCEL AT ANY TIME

  • MUST-HAVES

    PLASMAGLO LED FACE AND JOWL MASK

    RajaniMD Plasma Restore GLO Volufiline cream product image for skin volume and firmness

    PLASMA RESTORE GLO VOLUFILINE CREAM

    RajaniMD retinol A serum product image for anti-aging skincare

    RETINOL A SERUM

    FEATURED
    • MUST-HAVES
    • BEST ROUTINES
    • SUMMER ROUTINES
  • SHOP
    FEATURED
    • BEST SELLERS
    • COURSES
    • FOR MEN
    • K-BEAUTY LINE
    • ESSENTIALS
    • EXTRAS
    • OFFERS
    DEVICES
    • ALL
    • CRYOGLO ROLLER
    • LED GUA SHA
    • LED FACE AND JOWL MASK
    • LED HALO HAIR, FACE AND NECK MASK
    • LED LIGHT THERAPY
    • LED LIP & MOUTH DEVICE
    • MICRO-NEEDLE ROLLER
    • MICRO-NEEDLE COLLECTION
    • NEWA RF AGE REPAIR
    • PEMF TECHNOLOGY
    • PLASMAGLO BOOST VIBRATION
    • PLASMASOMES MICRO-NEEDLE KIT
    • UNDER EYE DUO GLO
    SKINCARE
    • ALL
    • EXFOLIANTS + TONERS
    • KOREAN SKINCARE
    • EYES
    • LIPS
    • LIPO FILLING CREAM
    • MOISTURIZERS
    • NECK
    • NIGHT CREAMS
    • PEEL PADS
    • SERUMS + VIT C
    • SPF SUNSCREEN
    • SPICULE SKINCARE
    WELLNESS
    • ALL
    • 100% BLACK GARLIC
    • COLLAGEN POWDER
    • CREATINE GUMMIES
    • CREATINE MONOHYDRATE POWDER
    • ELECTROGLO ELECTROLYTES
    • KRILL OIL SOFTGELS
    • K2+D3 CAPSULES
    • PLASMA RESTORE GLO GUMMIES
    • SLEEP EXTREME CAPSULES
    • TURMERIC CAPSULES
    • WOMEN'S VITALITY BLEND
    ROUTINE FOR
    • COMPLEXION/PORE SIZE
    • CONTOURING/SCULPTING
    • DARK SPOTS
    • DRY/SENSITIVE SKIN
    • EYES
    • FACIAL FAT LOSS
    • HEALTHY AGING
    • LOWER FACE/JOWLS
    • NECK
    • REDNESS
    • UNEVEN SKIN TONE
    • VERTICAL LIP LINES
  • LEARN
    Meet Dr. Rajani portrait image introducing the founder of RajaniMD beauty and wellness
    RajaniMD doctor’s blog icon image representing skincare articles and expert insights
    EXPLORE
    • OUR PHILOSOPHY
    • GIVING BACK
    • SUSTAINABILITY
    • RAJITV
  • ROUTINES
    RajaniMD skincare routine guide image for step-by-step skincare planning
    RajaniMD skincare routine graphic highlighting 'Start Here' for personalized beauty and wellness recommendations
    ROUTINES
    • SKIN TIPS & TRICKS
    • TIGHTEN YOUR LOOSE SKIN
    • ADDRESS UNDER EYE AGING NOW
  • SKIN QUIZ
Rajani MD Rx Rajani MD clinically proven skincare and aesthetics logo
Login Gift Cards
0
      • MUST-HAVES
      • BEST ROUTINES
      • SUMMER ROUTINES

    PLASMAGLO LED FACE AND JOWL MASK

    RajaniMD Plasma Restore GLO Volufiline cream product image for skin volume and firmness

    PLASMA RESTORE GLO VOLUFILINE CREAM

    RajaniMD retinol A serum product image for anti-aging skincare

    RETINOL A SERUM

      • BEST SELLERS
      • COURSES
      • FOR MEN
      • K-BEAUTY LINE
      • ESSENTIALS
      • EXTRAS
      • OFFERS
      • ALL
      • CRYOGLO ROLLER
      • LED GUA SHA
      • LED FACE AND JOWL MASK
      • LED HALO HAIR, FACE AND NECK MASK
      • LED LIGHT THERAPY
      • LED LIP & MOUTH DEVICE
      • MICRO-NEEDLE ROLLER
      • MICRO-NEEDLE COLLECTION
      • NEWA RF AGE REPAIR
      • PEMF TECHNOLOGY
      • PLASMAGLO BOOST VIBRATION
      • PLASMASOMES MICRO-NEEDLE KIT
      • UNDER EYE DUO GLO
      • ALL
      • EXFOLIANTS + TONERS
      • KOREAN SKINCARE
      • EYES
      • LIPS
      • LIPO FILLING CREAM
      • MOISTURIZERS
      • NECK
      • NIGHT CREAMS
      • PEEL PADS
      • SERUMS + VIT C
      • SPF SUNSCREEN
      • SPICULE SKINCARE
      • ALL
      • 100% BLACK GARLIC
      • COLLAGEN POWDER
      • CREATINE GUMMIES
      • CREATINE MONOHYDRATE POWDER
      • ELECTROGLO ELECTROLYTES
      • KRILL OIL SOFTGELS
      • K2+D3 CAPSULES
      • PLASMA RESTORE GLO GUMMIES
      • SLEEP EXTREME CAPSULES
      • TURMERIC CAPSULES
      • WOMEN'S VITALITY BLEND
      • COMPLEXION/PORE SIZE
      • CONTOURING/SCULPTING
      • DARK SPOTS
      • DRY/SENSITIVE SKIN
      • EYES
      • FACIAL FAT LOSS
      • HEALTHY AGING
      • LOWER FACE/JOWLS
      • NECK
      • REDNESS
      • UNEVEN SKIN TONE
      • VERTICAL LIP LINES
      • OUR PHILOSOPHY
      • GIVING BACK
      • SUSTAINABILITY
      • RAJITV
    Meet Dr. Rajani portrait image introducing the founder of RajaniMD beauty and wellnessRajaniMD doctor’s blog icon image representing skincare articles and expert insights
      • SKIN TIPS & TRICKS
      • TIGHTEN YOUR LOOSE SKIN
      • ADDRESS UNDER EYE AGING NOW
    RajaniMD skincare routine guide image for step-by-step skincare planningRajaniMD skincare routine graphic highlighting 'Start Here' for personalized beauty and wellness recommendations
  • SKIN QUIZ
Account

Cart

Your cart is empty

Start shopping
Krill Oil vs Fish Oil: Phospholipid Omega-3s, Astaxanthin, and Why It Matters for Skin Reading PlasmaSOMES™ and Home Micro-needling: How to Use Micro-needling Kits Safely 6 minutes Next LED Light Therapy Mask Color Chart: Exactly What Each Color Targets
  1. Home
  2. Spotlight
  3. Plasmasomes™ and home micro-needling: how to use micro-needling kits safely

PlasmaSOMES™ and Home Micro-needling: How to Use Micro-needling Kits Safely

Share

Micro-needling used to be something you only got in a clinic chair. Now you can make a version of it at home in the evening in about 10 minutes. The results can be impressive when you do it correctly. They can also irritate your skin when you do it wrong.

This blog covers what a micro-needling kit actually does, what plasmaSOMES are, and how to use the entire system safely to achieve smoother, firmer skin without the guesswork.

What a Micro-needling Kit Does

Micro-needling works by creating tiny, controlled channels in the skin's surface. Your body reads those micro-channels as something to repair, so it ramps up collagen and elastin, the two proteins that keep skin firm and bouncy.

Two things happen at once. Your skin triggers a natural renewal response, and the channels allow active serums to penetrate far more deeply than they would on intact skin. That second part matters. A good serum sitting on top of closed skin only does so much. The same serum applied during micro-needling reaches the layers where it can actually work.

The plasmaSOMES Micro-Needle Kit is built around exactly this idea. It pairs a medical-grade roller with a regenerative serum and a short training course, so you are not improvising.

Woman using the Rajani MD plasmaSOMES™ Micro-Needle Kit as part of an at-home skincare routine.

Micro-needling Benefits Worth Knowing

When done consistently, at-home micro-needling can help soften the look of fine lines and wrinkles, improve firmness in loose or crepey areas, refine texture and the appearance of pores, even out tone, including the appearance of sunspots and post-acne marks, and boost how well your serums absorb. These are gradual changes, not overnight ones. Most people start noticing smoother texture within a few weeks of regular use.

What Are plasmaSOMES?

Here is where the Rajani MD system differs from a basic roller.

PlasmaSOMES are biomimetic nanoparticles. In plain terms, they are lab-made messengers designed to copy the helpful signaling of exosomes, without using any human or animal-derived material. That makes them vegan, stable at room temperature, and easier to manufacture to a consistent standard. 

The PlasmaSOMES serum/solution also carry specialized hyaluronic acid, niacinamide, tranexamic acid, and targeted peptides. Tranexamic acid helps brighten and address stubborn discoloration, which is why the formula supports both tone and texture.

The idea of micro-needling with plasmaSOMES is simple: create the channels, then deliver intelligent ingredients into them.

Rajani MD plasmaSOMES™ Micro-Needle Kit with a three-month supply of skincare solution.

How to use a micro-needling kit safely at home

Safe technique comes down to hygiene, the right needle depth, and not overdoing frequency.

1. Sanitize first. Soak the roller in rubbing alcohol before and after every session, then run hot water over it to rinse off residue. A clean roller is the single most important safety step.

2. Start clean. Wash your face and remove all makeup and oils. Micro-needling over dirty skin pushes bacteria and product into fresh channels.

3. Use the right depth. The plasmaSOMES Micro-Needle Roller is 0.25mm, chosen on purpose. A 0.25mm roller is generally considered a superficial at-home option, but it still requires careful use. Follow all hygiene instructions, avoid irritated or broken skin, and do not use over active breakouts, open areas, or freshly treated skin unless directed by your provider. Resist the urge to buy a longer, more aggressive roller for “better” results, since deeper at-home needling can increase the risk of irritation or injury. 

4. Roll with a plan. Apply a thin layer of serum, then roll gently back and forth: horizontally, vertically, and diagonally over each area. Let the weight of the roller do the work.

5. Reapply and rest. Apply another thin layer of solution when you finish. Doing this in the evening lets your skin heal overnight, protected from sun and pollution. By morning you can return to your normal routine.

How Often: Start with once a week. As your skin adjusts, move to two or three evenings per week. Replace the roller after about 25 treatments or 60 days, since worn needles are less safe and less effective.

Getting More From Every Session

A few easy additions help. Some people use the PlasmaGLO Boost vibration tool to work serum in evenly. On non-needling nights, red light from an LED device supports the same collagen pathways. Sealing skin afterward with the Plasma Restore GLO Volufiline Cream locks in hydration and supports volume. If you want the device and the cream together at a saving, the Plasma Pairing set bundles them.

New to building a device regimen? The routine for healthy aging and the skin quiz are good starting points.

RajaniMD plasmaSOMES Micro-Needle Kit for at-home microneedling and skin rejuvenation.

plasmaSOMES Micro-Needle Kit

$250.00
Shop now
RajaniMD Plasma Restore GLO Volufiline Cream for plumping, hydration, firmness, and facial volume support.

Plasma Restore GLO Volufiline Cream

$285.00
Shop now
RajaniMD PlasmaGLO Boost vibration device designed to complement skincare and support a radiant complexion.

PlasmaGLO Boost

$39.00
Shop now

Frequently Asked Questions

Does at-home micro-needling hurt? 

With a 0.25mm roller, most people feel light pressure rather than pain, and no numbing cream is needed.

How soon will I see results? 

Many users notice smoother texture within 4 to 6 weeks of consistent use.

Can I micro-needle every day? 

No. We recommend micro-needling once a week in the evening.

Is it safe for darker skin tones? 

Yes. The system is designed for all skin types and skin tones, with ingredients chosen to support an even tone.

Smarter at Home, Not Riskier

Home micro-needling rewards patience and good habits. Keep the roller clean, stick to 0.25mm, respect the frequency, and let plasmaSOMES do the heavy lifting in the channels you create. 

Ready to start? Explore the full micro-needle collection and pick the kit that fits your goals.

Disclaimer: This article is educational and not medical advice. Patch test new products and consult your provider with any concerns.

References:

Litchman, Graham, et al. "Micro-needling." StatPearls, StatPearls Publishing, 2022. National Center for Biotechnology Information, www.ncbi.nlm.nih.gov/books/NBK459344/.

Avci, Pinar, et al. "Low-Level Laser (Light) Therapy (LLLT) in Skin: Stimulating, Healing, Restoring." Seminars in Cutaneous Medicine and Surgery, vol. 32, no. 1, 2013, pp. 41-52. PubMed Central, www.ncbi.nlm.nih.gov/pmc/articles/PMC4126803/.

Tags
  • micro-needling
  • Plasma Restore GLO Volufiline Cream
  • PlasmaGLO Boost
  • plasmasomes
  • plasmaSOMES Micro-Needle Kit

DISCLAIMER: This video does not contain any medical or health related diagnosis or treatment advice. Content provided on this YouTube Channel is for informational purposes only. For any medical or health related advice, please consult with a physician or other healthcare professionals. Further, information about specific products or treatments within this video are not intended to diagnose, treat, cure or prevent disease.

Recommended Products
BEST SELLER RajaniMD PlasmaGLO LED face and jowl mask for facial rejuvenation and skin tightening
PlasmaGLO™ LED Face and Jowl Mask

RED LIGHT THERAPY - FULL FACE AND JOWL

Sale price$425.00
$1.18 /oz
plasmaSOMES™ / Micro-Needle Kit --- 3 month supply plasmaSOMES™ / Micro-Needle Kit --- 3 month supply
plasmaSOMES™ / Micro-Needle Kit --- 3 month supply

THE FIRST-OF-ITS-KIND ALTERNATIVE TO EXOSOMES

Sale price$325.00
Multi Collagen Peptides Powder Multi Collagen Peptides Powder
Multi Collagen Peptides Powder

STRUCTURAL BEAUTY SUPPORT

Sale price$69.00

Stay up-to-date

Similar articles

Microplastics Are In Your Body! 5 Tips To Limit Your Exposure
Anti Aging Supplements and Foods

Microplastics Are In Your Body! 5 Tips To Limit Your Exposure

HAIR LOSS WITH OZEMPIC
Ask Dr Rajani

HAIR LOSS WITH OZEMPIC

NEW STUDY Findings 🥩 KETO DIET Vs MEDITERRANEAN DIET 🥬// Keto
healthy diet

NEW STUDY Findings 🥩 KETO DIET Vs MEDITERRANEAN DIET 🥬// Keto

Invalid password
Enter

SHOP

  • BEST SELLERS
  • COLLECTIONS
  • OFFERS
  • GIFT CARDS
  • LOCATOR
  • WHOLESALE

SUPPORT

  • CONTACT US
  • SHIPPING + RETURNS
  • HELP CENTER
  • ACCOUNT LOGIN
  • IN THE MEDIA
  • PRESS INQUIRIES

STORE

  • Rx INSIDER REWARDS
  • SUBSCRIBE AND SAVE
  • REFER FRIENDS
  • HSA/FSA ELIGIBILITY
  • WE REWARD HEROES
  • AMBASSADORS
  • OUR PHILOSOPHY
  • SUSTAINABILITY

GIVING BACK

DON'T MISS OUT!

        
Accessibility View
For Your Best Life

© 2026 RAJANI MD. ALL RIGHTS RESERVED. | TERMS | PRIVACY POLICY | EU WITHDRAWAL
The information on this website is not intended to diagnose, treat, cure, or prevent any disease. The content may not be reproduced in any way.