Skip to content

FREE SHIPPING AVAILABLE ON US ORDERS*

FREE GIFT WITH EVERY ORDER!

SAVE WITH SUBSCRIPTIONS. RESCHEDULE, SKIP, CANCEL AT ANY TIME

  • MUST-HAVES

    PLASMAGLO LED FACE AND JOWL MASK

    RajaniMD Plasma Restore GLO Volufiline cream product image for skin volume and firmness

    PLASMA RESTORE GLO VOLUFILINE CREAM

    RajaniMD retinol A serum product image for anti-aging skincare

    RETINOL A SERUM

    FEATURED
    • MUST-HAVES
    • BEST ROUTINES
    • SUMMER ROUTINES
  • SHOP
    FEATURED
    • BEST SELLERS
    • COURSES
    • FOR MEN
    • K-BEAUTY LINE
    • ESSENTIALS
    • EXTRAS
    • OFFERS
    DEVICES
    • ALL
    • CRYOGLO ROLLER
    • LED GUA SHA
    • LED FACE AND JOWL MASK
    • LED HALO HAIR, FACE AND NECK MASK
    • LED LIGHT THERAPY
    • LED LIP & MOUTH DEVICE
    • MICRO-NEEDLE ROLLER
    • MICRO-NEEDLE COLLECTION
    • NEWA RF AGE REPAIR
    • PEMF TECHNOLOGY
    • PLASMAGLO BOOST VIBRATION
    • PLASMASOMES MICRO-NEEDLE KIT
    • UNDER EYE DUO GLO
    SKINCARE
    • ALL
    • EXFOLIANTS + TONERS
    • KOREAN SKINCARE
    • EYES
    • LIPS
    • LIPO FILLING CREAM
    • MOISTURIZERS
    • NECK
    • NIGHT CREAMS
    • PEEL PADS
    • SERUMS + VIT C
    • SPF SUNSCREEN
    • SPICULE SKINCARE
    WELLNESS
    • ALL
    • 100% BLACK GARLIC
    • COLLAGEN POWDER
    • CREATINE GUMMIES
    • CREATINE MONOHYDRATE POWDER
    • ELECTROGLO ELECTROLYTES
    • KRILL OIL SOFTGELS
    • K2+D3 CAPSULES
    • PLASMA RESTORE GLO GUMMIES
    • SLEEP EXTREME CAPSULES
    • TURMERIC CAPSULES
    • WOMEN'S VITALITY BLEND
    ROUTINE FOR
    • COMPLEXION/PORE SIZE
    • CONTOURING/SCULPTING
    • DARK SPOTS
    • DRY/SENSITIVE SKIN
    • EYES
    • FACIAL FAT LOSS
    • HEALTHY AGING
    • LOWER FACE/JOWLS
    • NECK
    • REDNESS
    • UNEVEN SKIN TONE
    • VERTICAL LIP LINES
  • LEARN
    Meet Dr. Rajani portrait image introducing the founder of RajaniMD beauty and wellness
    RajaniMD doctor’s blog icon image representing skincare articles and expert insights
    EXPLORE
    • OUR PHILOSOPHY
    • GIVING BACK
    • SUSTAINABILITY
    • RAJITV
  • ROUTINES
    RajaniMD skincare routine guide image for step-by-step skincare planning
    RajaniMD skincare routine graphic highlighting 'Start Here' for personalized beauty and wellness recommendations
    ROUTINES
    • SKIN TIPS & TRICKS
    • TIGHTEN YOUR LOOSE SKIN
    • ADDRESS UNDER EYE AGING NOW
  • SKIN QUIZ
Rajani MD Rx Rajani MD clinically tested skincare and aesthetics logo
Login Gift Cards
0
      • MUST-HAVES
      • BEST ROUTINES
      • SUMMER ROUTINES

    PLASMAGLO LED FACE AND JOWL MASK

    RajaniMD Plasma Restore GLO Volufiline cream product image for skin volume and firmness

    PLASMA RESTORE GLO VOLUFILINE CREAM

    RajaniMD retinol A serum product image for anti-aging skincare

    RETINOL A SERUM

      • BEST SELLERS
      • COURSES
      • FOR MEN
      • K-BEAUTY LINE
      • ESSENTIALS
      • EXTRAS
      • OFFERS
      • ALL
      • CRYOGLO ROLLER
      • LED GUA SHA
      • LED FACE AND JOWL MASK
      • LED HALO HAIR, FACE AND NECK MASK
      • LED LIGHT THERAPY
      • LED LIP & MOUTH DEVICE
      • MICRO-NEEDLE ROLLER
      • MICRO-NEEDLE COLLECTION
      • NEWA RF AGE REPAIR
      • PEMF TECHNOLOGY
      • PLASMAGLO BOOST VIBRATION
      • PLASMASOMES MICRO-NEEDLE KIT
      • UNDER EYE DUO GLO
      • ALL
      • EXFOLIANTS + TONERS
      • KOREAN SKINCARE
      • EYES
      • LIPS
      • LIPO FILLING CREAM
      • MOISTURIZERS
      • NECK
      • NIGHT CREAMS
      • PEEL PADS
      • SERUMS + VIT C
      • SPF SUNSCREEN
      • SPICULE SKINCARE
      • ALL
      • 100% BLACK GARLIC
      • COLLAGEN POWDER
      • CREATINE GUMMIES
      • CREATINE MONOHYDRATE POWDER
      • ELECTROGLO ELECTROLYTES
      • KRILL OIL SOFTGELS
      • K2+D3 CAPSULES
      • PLASMA RESTORE GLO GUMMIES
      • SLEEP EXTREME CAPSULES
      • TURMERIC CAPSULES
      • WOMEN'S VITALITY BLEND
      • COMPLEXION/PORE SIZE
      • CONTOURING/SCULPTING
      • DARK SPOTS
      • DRY/SENSITIVE SKIN
      • EYES
      • FACIAL FAT LOSS
      • HEALTHY AGING
      • LOWER FACE/JOWLS
      • NECK
      • REDNESS
      • UNEVEN SKIN TONE
      • VERTICAL LIP LINES
      • OUR PHILOSOPHY
      • GIVING BACK
      • SUSTAINABILITY
      • RAJITV
    Meet Dr. Rajani portrait image introducing the founder of RajaniMD beauty and wellnessRajaniMD doctor’s blog icon image representing skincare articles and expert insights
      • SKIN TIPS & TRICKS
      • TIGHTEN YOUR LOOSE SKIN
      • ADDRESS UNDER EYE AGING NOW
    RajaniMD skincare routine guide image for step-by-step skincare planningRajaniMD skincare routine graphic highlighting 'Start Here' for personalized beauty and wellness recommendations
  • SKIN QUIZ
Account

Cart

Your cart is empty

Start shopping
plasmaSOMES™ MicroNeedling Solution (refill) $295.00
/
  1. Home
  2. plasmaSOMES™ MicroNeedling Solution (refill)
plasmaSOMES™ MicroNeedling Solution (refill)
plasmaSOMES™ MicroNeedling Solution (refill)
plasmaSOMES™ MicroNeedling Solution (refill)
plasmaSOMES™ MicroNeedling Solution (refill)
plasmaSOMES™ MicroNeedling Solution (refill)
plasmaSOMES™ MicroNeedling Solution (refill)
Rajani MD
4.6
Rated 4.6 out of 5 stars
14 Reviews

plasmaSOMES™ MicroNeedling Solution (refill)

FG icon
Step 2: Treat
Moon and stars icon symbol representing nighttime or evening skincare routine
Sale price$295.00
Rajani MD
4.6
Rated 4.6 out of 5 stars
14 Reviews

plasmaSOMES™ MicroNeedling Solution (refill)

FG icon
Step 2: Treat
Moon and stars icon symbol representing nighttime or evening skincare routine
Sale price$295.00
Quantity:
Order today and product will ship out in 1-2 business days Processing usually takes 1-2 business days. During promotions, holidays, or high-volume periods, processing may take longer.

WAYS TO SAVE:

Education/Military/Healthcare – save $29.50. Learn more.

After years of research and engineering by world-reknowned scientist, Dr. Rajani proudly presents Plasmasomes™ - a revolutionary skin cell solution system that combines advanced MOCRA certified nanoparticle technology signals, Tranexamic Acid and Specialized Hyaluronic Acid, with professional micro-needling to deliver real results. This first-of-its-kind alternative to exosomes is scientifically proven to remind your skin to act younger. To reduce wrinkles, tighten skin, and improve clarity - all WITHOUT USING human-derived materials traditionally found in exosomes and growth factors. In fact its Vegan!!

KEY BENEFITS:
Reduces fine lines and wrinkles
Tightens loose, crepey skin
Improves skin clarity and brightness
Treats stubborn melasma and sunspots
Minimizes redness and acne scarring
Works on both face and neck
INGREDIENTS

Water (Aqua), Benzyl Alcohol, Dehydroacetic Acid, Hyaluronic Acid, Tranexamic Acid, dl-Panthenol, Niacinamide, DOTAP, DSPC, DSPE, DSPE PEG, Sodium Chloride, Disodium Phosphate, Potassium Phosphate, Potassium Chloride, Phosphatidylcholine, Phosphatidylserine, Sphingomyelin, Cholesterol, Mannitol, Trehalose, sh-Polypeptide-14 (NGF), sh-Polypeptide-10 (KGF-2), sh-Polypeptide-66 (SIRT-1), sh-Polypeptide-67 (SIRT-2), sh-Polypeptide-2 (TRX), sh-Polypeptide-5 (TGF-b3), sh-Polypeptide-58 (TIMP-1)

TIPS FROM DR. RAJANI

Watch my full video playlist for plasmaSOMES here:

https://www.youtube.com/watch?v=h5iENUy0LZQ&list=PLg28Mxv8Eucf7kbZiiXOnqNVdRUdWuANl

X

FAQS

WHEN SHOULD I MICRONEEDLE?

Ultimately you can do Home Microneedling any time that works for you. For optimal comfort and ease, we recommend needling in the evening before bed. 1. Apply a thin layer of PlasmaSomes solution. 2. Needle. 3. Apply another thin layer of solution and go to sleep. As you rest, your skin is protected from environmental irritants, allowing it to naturally heal and regenerate. Then the next morning you can go about your normal routine without worry.

What makes plasmaSOMES different from traditional exosomes?

PlasmaSOMES are biomimetic nanoparticles that replicate exosome function without using human cells, offering better manufacturing control and stability while maintaining powerful regenerative benefits.

Is this product FDA approved?

PlasmaSOMES are produced in an FDA-listed laboratory and are MOCRA certified. While not FDA approved (as cosmetics don't require FDA approval), they meet all safety and quality standards.

How is this vegan if it has stem cell technology?

PlasmaSOMES use innovative biomimetic technology to replicate the benefits of stem cells without using any animal or human-derived ingredients, making it 100% vegan.

What is the recommended storage method?

PlasmaSOMES are stable at room temperature, requiring no special storage conditions.

Is it safe for all skin types?

Yes! The system is: Safe for all skin types and colors; Specifically formulated to prevent pigmentation issues; Includes targeted ingredients for melasma protection; Supports rather than compromises your skin barrier

more faqs
×
4.6
Rated 4.6 out of 5 stars
Based on 14 reviews
5
Rated out of 5 stars
12
4
Rated out of 5 stars
1
3
Rated out of 5 stars
0
2
Rated out of 5 stars
0
1
Rated out of 5 stars
1
93%would recommend this product
Write a Review (Opens in a new window)
14 reviews
  • TC
    Terri C.
    Verified Buyer
    Rated 5 out of 5 stars
    8 months ago
    Glass skin!

    Love that this is so easy to use and results immediate

    Was this helpful?
  • JJ
    Julie J.
    Verified Buyer
    Rated 4 out of 5 stars
    9 months ago
    Plasmasome

    Like it a lot, havnt really seen any big difference though.

    Goes a long way. Might buy again, but not sure yet.

    Was this helpful?
  • EV
    Elena V.
    Verified Buyer
    Rated 5 out of 5 stars
    9 months ago
    Grateful For Exosome Substitute

    I learned from Dr Rajani about the potential risks from exosomes, so I’m so thankful he’s offered us a safe alternative with these PlasmaSomes. Just roll the area, micro needle, roll again. There is no stinging or uncomfortable sensation from the PlasmaSomes entering the micro channels made by the micro needle roller. I’ve had great success with improvements in skin firmness, tightening and lifting and I’m nearly 65.

    Was this helpful?
  • SM
    Sullivan M.
    Verified Reviewer
    Rated 1 out of 5 stars
    10 months ago
    Not worth the money

    It’s a roller and hyaluronic acid. So extremely overpriced

    Was this helpful?
    RM Profile picture for Rajani MD Beauty and Wellness
    Rajani MD Beauty and Wellness
    10 months ago

    Thank you for sharing your feedback, Melissa. We understand how important value is when choosing skincare. While PlasmaSomes may appear similar to a basic hyaluronic acid serum, it’s actually a next-generation formula that combines Hyaluronic Acid with advanced nanolipid delivery technology designed to carry bioactive ingredients deeper into the skin—supporting collagen renewal and repair.

    Pairing it with a precision microneedling roller helps to enhance absorption and results. When used consistently and as part of a complete skincare and wellness routine, most users see visible improvement in firmness and skin texture over time. We truly appreciate you giving it a try and sharing your thoughts.

  • M
    Marie
    Verified Buyer
    Rated 5 out of 5 stars
    11 months ago
    Amazing

    My first photo you see that red area on face, a long time ago it looked like a heart shaped blood spot and I paid $150 twenty years ago to get it removed well they told me it take allot more appointments so I was like one enough forget it. I got this product PlasmaSomes and have been using it for 4 months now with my micro needle stamper and today I noticed it’s almost gone Wow a great surprise!! I wasn’t expecting this blood spot to ever go away so it’s a plus!

    Was this helpful?
  • SM
    Shayee M.
    Verified Buyer
    Rated 5 out of 5 stars
    11 months ago
    Very nice

    I’ve been using the microneedling kit for 4 months now, once every 7 days. It’s very easy to use and super convenient to clean (which is especially important to me). You can really tell it’s a high-quality product.

    I naturally have rather dry skin, and I do notice that my skin feels a bit drier the next day. But I absolutely love the changes in my skin. I’m very satisfied and will definitely continue ordering.

    Thank you so much!

    Was this helpful?
  • I Profile picture for Isol
    Isol
    Verified Buyer
    Rated 5 out of 5 stars
    12 months ago
    First impression

    Today I microneedled for the first time with the PlasmaSomes. They are easy to use, not messy, and conveniently packaged. They also have a long shelf life, which I love.. But the thing I love the most is that is made by Dr. Rajani, whom I trust so much, so I know that I'm putting on my skin and body products that are safe for me. I use so many of Dr. Rajani's products that my friends call me Mrs. Rajani. :D I plan to do my next microneedling session with my PlasmaSomes at a deeper level.

    Was this helpful?
  • JC
    John C.
    Verified Buyer
    Rated 5 out of 5 stars
    1 year ago
    Love this Product

    Micro needling has added volume to my face. I love this.

    Was this helpful?
Loading...
Loading...
Show More
Invalid password
Enter

SHOP

  • BEST SELLERS
  • COLLECTIONS
  • OFFERS
  • GIFT CARDS
  • LOCATOR
  • WHOLESALE

SUPPORT

  • CONTACT US
  • SHIPPING + RETURNS
  • HELP CENTER
  • ACCOUNT LOGIN
  • IN THE MEDIA
  • PRESS INQUIRIES

STORE

  • Rx INSIDER REWARDS
  • SUBSCRIBE AND SAVE
  • REFER FRIENDS
  • HSA/FSA ELIGIBILITY
  • WE REWARD HEROES
  • AMBASSADORS
  • OUR PHILOSOPHY
  • SUSTAINABILITY

GIVING BACK

DON'T MISS OUT!

        
Accessibility View
For Your Best Life

© 2026 RAJANI MD. ALL RIGHTS RESERVED. | TERMS | PRIVACY POLICY | EU WITHDRAWAL
The information on this website is not intended to diagnose, treat, cure, or prevent any disease. The content may not be reproduced in any way.

 

Your friend has gifted you a reward!

Your reward!

Claim your Reward for your Ocean Bottle Purchase and Start Making an Impact Today.
Here is your coupon code
Enter your email address to receive your $10 reward.