What makes plasmaSOMES different from traditional exosomes?
2500+ Satisfied Customers
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Unlock Clinical-Level Skin Transformation at Home with the RajaniMD plasmaSOMES™ At-home Microneedle Kit
Target fine lines, dull texture and uneven tone
Virtually painless • minimal downtime • science-backed results
Designed for safe, at-home use
Payment Plan Available*
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Why plasmaSOMES Works
PlasmaSOMES™ goes where your creams can’t — delivering powerful skincare ingredients beneath the surface, where they matter most. Our microneedling technology enhances absorption and supercharges your favorite serums for visible transformation.
What You’ll Notice
Smoother, Plumper Skin
Stimulates gentle micro-channels to support natural collagen and elastin for a visibly firmer complexion.
Enhanced Radiance & Glow
Boosts serum penetration deep into your skin — improving texture, tone, and overall luminosity.
Reduced Fine Lines & Uneven Texture
Delivers actives beyond the surface for results that feel as good as they look.
Cost-Effective Alternative to Clinical Treatments
Professional-inspired results you can achieve at home in just minutes.
2030 science available today
The Power Inside plasmaSOMES Serum
Our microneedling results are only as good as what you deliver into the skin. PlasmaSOMES Serum is formulated with regenerative, collagen-supporting, and barrier-repair ingredients designed to work with microchannel technology — not irritate it. Here’s what makes it exceptional:
Growth Factor–Rich Exosomes (plasmaSOMES Technology)
Why it matters: Exosomes are advanced cellular messengers that help signal skin to repair, renew, and produce more collagen and elastin.
What they do:
Support visible skin rejuvenation.
Improve the look of fine lines and laxity.
Enhance overall skin vitality and resilience.
When delivered through microchannels, these regenerative messengers can work more efficiently where renewal begins.
Multi-Molecular Hyaluronic Acid
Why it matters: Hydration is essential after microneedling. Different molecular weights allow hydration at multiple skin levels.
What it does:
Instantly plumps the appearance of fine lines
Replenishes moisture after treatment
Supports a smoother, dewier glow
Peptide Complex
Why it matters: Peptides act as signal molecules that encourage firmer-looking skin.
What they do:
Support the appearance of collagen and elastin
Improve visible skin density
Promote a firmer, smoother texture
Barrier-Support Complex
(Panthenol + Soothing Botanicals)
Why it matters: After microneedling, calming support is key.
What they do:
Helps reduce visible redness
Reinforces the skin barrier
Supports recovery and comfort
Real People. Real Results
Trusted by Professionals
Recommended by doctors, clinical providers, nurses, estheticians, and other practitioners :: backed by science
I’m intentional about everything I use in practice, and RajaniMD aligns beautifully with my regenerative, skin-first philosophy. Beauty begins holistically starting from the inside out in order to GLO. My personal favorites are the Gua Sha for sculpting and lymphatic flow, paired with PlasmaGLO to support collagen and inflammation internally. I recommend this to all of my patients especially when prepping for EZGEL PRF. This is true inside-out regeneration at its finest.
Amy Lynn, RN CANS
Glo Derma Aesthetics and Wellness
As a medical provider, I value skin care products and supplements that go beyond minimal standards and truly prioritize sourcing integrity and rigorous quality control throughout production. RajaniMD’s products reflect that level of commitment.
Claire Francoeur, FNP
Whitefish Creative Aesthetics
If you asked me who my mentor is, the answer would be hands down, Dr. Anil Rajani. His social media presence is incredible, but more importantly, he continuously learns from and engages with his audience while staying on the cutting edge of aesthetic medicine. I resonate deeply with his mindset because we both believe in thinking outside the box and aren’t afraid to take things to the next level — and that’s truly where the magic happens!
Donna Gonzalez, APRN
Artisan Face and Body
I’m proud to say I was one of Dr. Anil Rajani’s very first affiliates — and from day one, I knew his products were special. Every formula and device he offers is made here in the United States in small batches, with Dr. Rajani, who is deeply involved in development and quality control.
Heather Speert, RN, CANS
Spirited Aesthetics
We love RajaniMD because it represents the perfect balance between innovation, efficacy, and elegance in medical-grade skincare. The formulations are thoughtfully designed, clinically sound, and consistently deliver results our patients can see and feel. RajaniMD is a natural extension of the high-level aesthetic and wellness care we provide at Andrews Medical & Aesthetics.
Dr. Nildaliz Andrews, MD
Andrews Medical & Aesthetics
I love incorporating RajaniMD products because they are designed for practitioners who value measurable results, practical use, and outcomes that patients can maintain anywhere, including on-the-go.
Irena Ivanova Panayotov MSN, FNP-C
Glamour Me Medical
As a physician-run medical spa, we take research seriously. With so much hype in the aesthetics industry, we want our clients to trust that every product and treatment we offer is backed by real science. We chose Dr. Rajani’s PlasmaGlo LED masks because the technology is proven—and because the added features align with what our clients value. Rajani has been incredibly supportive and responsive, giving us full confidence that we’re offering something truly effective.
Kay Theyerl, MD
RefineMD
As a physician specializing in preventive and functional medicine for over a decade, I focus on empowering patients to achieve optimal health through holistic, evidence-based solutions. Dr. Anil Rajani’s RajaniMD product line has become a cornerstone in my practice for patients seeking to enhance their skin’s vitality while supporting overall wellness.
Carrie F. Blades, MD
Blades Wellness & Aesthetics
Chris L. - Verified Buyer
"Best Product"
Glow glow glow - a game changer for me!!!
Trusted Daily By Our Community
BRILLIANT
What a wonderful product Dr. Rajani created. I love and enjoy using the plasmaSomes… What a Fabulous difference it’s made to my skin care routine…My skin is gloriously soft the next day and looks beautiful and radiant. 🙌.
Donna A.
Verified Buyer
Best Peptides for your skin!
I have tested many high end products and the Plasmasomes is one of the most efficient being plant based peptides. My skin started to look smoother after day 3 and I have seen improvent on my neck as well. The dermaroller is gentle and you barely feel it. Easy to use. I'm loving them! 💖
Vivian D.
Verified Buyer
Best at home micro needling kit!!!
I’ve been using this kit for a few weeks now and although it’s only .25, I get a very deep treatment with it!! I use his hyaluronic acid serum and volufiline cream after bc I get really dry after micro-needling. I’m going to start putting the exosome and or the pdrn mask on after now that he has those!
Whitney A.
Verified Buyer
revolutionary skin cell solution system
The plasmaSOMES Advantage
RajaniMD plasmaSOMES
VS
Traditional Exosomes
Source
100% Vegan
Human-derived
Stability
Room temperature
Requires freezing
Cost per treatment
$30-$50
$550-$1500
Quality control
Precise Engineering
Variable
Safety profile
Enhanced
Variable
4.9/5
Based on Real Customer Reviews
delivering real results
Frequently Asked Questions
PlasmaSOMES are biomimetic nanoparticles that replicate exosome function without using human cells, offering better manufacturing control and stability while maintaining powerful regenerative benefits.
What are the ingredients?
Water (Aqua), Benzyl Alcohol, Dehydroacetic Acid, Hyaluronic Acid, Tranexamic Acid, dl-Panthenol, Niacinamide, DOTAP, DSPC, DSPE, DSPE PEG, Sodium Chloride, Disodium Phosphate, Potassium Phosphate, Potassium Chloride, Phosphatidylcholine, Phosphatidylserine, Sphingomyelin, Cholesterol, Mannitol, Trehalose, sh-Polypeptide-14 (NGF), sh-Polypeptide-10 (KGF-2), sh-Polypeptide-66 (SIRT-1), sh-Polypeptide-67 (SIRT-2), sh-Polypeptide-2 (TRX), sh-Polypeptide-5 (TGF-b3), sh-Polypeptide-58 (TIMP-1)
Is this product FDA approved?
PlasmaSOMES are produced in an FDA-listed laboratory and are MOCRA certified. While not FDA approved (as cosmetics don't require FDA approval), they meet all safety and quality standards.
How is this vegan if it has stem cell technology?
PlasmaSomes use innovative biomimetic technology to replicate the benefits of stem cells without using any animal or human-derived ingredients, making it 100% vegan.
What is the recommended storage method?
PlasmaSOMES are stable at room temperature, requiring no special storage conditions.
How long until I see results?
Individual results may vary, but most users report visible improvements in skin texture and tone within 4-6 weeks of consistent use.
TRUSTED BY 1. 7 MILLION
Because Results Matter, Dedicated to EDUCATE. EMPOWER. ELEVATE.
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We are here to answer your questions. Contact us at experts@RajaniMD.com.
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